Friday, 20 March 2020

Coronavirus: Australian scientists map how immune system fights virus


Researcher at a German pharmaceutical company demonstrates workflow testing for Covid-19 research.Image copyrightEPA
Scientists in Australia say they have identified how the body's immune system fights the Covid-19 virus.
Their research, published in Nature Medicine journal on Tuesday, shows people are recovering from the new virus like they would from the flu.
Determining which immune cells are appearing should also help with vaccine development, experts say.
Globally, authorities have confirmed more than 160,000 cases of the coronavirus and about 6,500 deaths.
"This [discovery] is important because it is the first time where we are really understanding how our immune system fights novel coronavirus," said study co-author Prof Katherine Kedzierska.
The research by Melbourne's Peter Doherty Institute for Infection and Immunity has been praised by other experts, with one calling it "a breakthrough".

What has been found?

Many people have recovered from Covid-19, meaning it was already known that the immune system can successfully fight the virus.
But for the first time, the research identified four types of immune cells which presented to fight Covid-19. 
They were observed by tracking a patient who had a mild-to-moderate case of the virus and no previous health issues.
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The 47-year-old woman from Wuhan, China, had presented to hospital in Australia. She recovered within 14 days.
Prof Kedzierska told the BBC her team had examined the "whole breadth of the immune response" in this patient.
Three days before the woman began to improve, specific cells were spotted in her bloodstream. In influenza patients, these same cells also appear around this time before recovery, Prof Kedzierska said.
Chest scans which showed the patient's lungs on Day 5 (left) had cleared by Day 10 (2)Image copyrightPETER DOHERTY INSTITUTE
Image captionChest scans showed the patient's lungs clearing after immune cells appeared
"We were very excited about our results - and the fact that we could actually capture the emergence of immune cells in the infected patient prior to clinical improvement," she told the BBC.
More than a dozen scientists worked around the clock for four weeks to deliver the analysis, she added.

How does this help?

Identifying when the immune cells kick in can help "predict the course of the virus", said Prof Bruce Thompson, dean of health sciences at Swinburne University of Technology.
"When you know when the various responses take place you can predict where you are in the recovery of the virus," Prof Thompson told the BBC.
Australia's Health Minister Greg Hunt said the finding could also help "fast-track" a vaccine and potential treatments for infected patients.
Media captionHow experts are developing a coronavirus vaccine
Prof Kedzierska said the next step for scientists was to determine why the immune response was weaker in worse cases.
"It is really key now to understand what is lacking or different in patients who have died or who have really severe disease - so we can understand how to protect them," she said.
The centre has since received additional funding from the Australian government as well as donations from businesses and Chinese billionaire Jack Ma.

Coronavirus: Iranians urged to stay home during holiday


Iranian women shop for Nowruz items at a market in Tehran (19 March 2020)Image copyrightAFP
Image captionIranian women shop for Nowruz items at a market in Tehran (19 March 2020)
Iran has urged people to stay at home during Nowruz, the Persian New Year, warning that the coronavirus disease is currently killing one person every 10 minutes.
"Considering this information, make a conscious decision concerning travel, days out and family visits,” the health ministry’s spokesman tweeted.
Tehran’s bazaars were busy and its roads filled with cars as Iranians prepared for Nowruz, which starts on Friday.
The country has reported 18,407 confirmed cases of Covid-19 and 1,284 related deaths in the past month.
The government has closed schools, universities and shrines, and banned cultural and religious gatherings in an attempt to contain the spread of the disease, but it has not imposed lockdowns.
Workers disinfect a street in Tehran to prevent the spread of the Covid-19 virus (18 March 2020)Image copyrightREUTERS
Image captionWorkers have been disinfecting streets in Tehran to try to prevent the spread of Covid-19
In a separate development on Thursday, Iran temporarily released an American citizen on medical grounds detained since 2018, US Secretary of State Mike Pompeo said.
Michael White, who is serving a 13-year sentence and whose family said he had cancer last year, is now in the custody of the Swiss embassy and will undergo medical testing and evaluation. 
“The United States will continue to work for Michael’s full release, as well as the release of all wrongfully detained Americans in Iran,” Mr Pompeo said.
On Thursday, health ministry spokesman Kianoush Jahanpour announced 149 new deaths from Covid-19 in the past 24 hours and another 1,046 cases.
At the current rate, he tweeted, "50 new cases of infection are detected every hour and one death recorded every 10 minutes".
Mr Jahanpour appealed to Iranians to stay at home and not travel during the two-week public holiday for Nowruz, when many families get together to celebrate, in order to help contain the spread of the virus.
On Wednesday, Deputy Health Minister Alireza Raisi expressed dismay that some people were not taking the disease “seriously”.
Photographs showed many people were still shopping in Tehran’s bazaars and driving their cars in apparent violation of a religious ruling from Supreme Leader Ayatollah Ali Khamenei forbidding “unnecessary” travel.
Media captionA woman wearing a face mask walking on a street in Iran
Earlier, the Iranian judiciary’s spokesman announced that about 10,000 prisoners, half of them serving sentences for “national security offences”, would be granted amnesties by the supreme leader to mark Nowruz.
The amnesty aimed to “reduce the number of prisoners in light of the sensitive situation in the country”, Gholamhossein Esmaili said, without explicitly referring to the Covid-19 outbreak. 
Amnesty International said it welcomed “the release of anyone detained as a prisoner of conscience" and called on the Iranian authorities to release all others in its jails.
The judiciary has already given 85,000 inmates two-week temporary releases in an effort to reduce the spread of Covid-19 through its crowded prisons.
Closed shops in CairoImage copyrightEPA
Image captionCafes in Egypt are closed from dawn until dusk
Many cases reported elsewhere in the Middle East have also been linked to Iran.
In Jordan, which has reported 35 cases of the Covid-19 virus, the army has begun imposing restrictions on access to the capital, Amman. 
Soldiers at checkpoints on main roads into the city were only allowing through goods vehicles and people travelling on authorised business. 
Egypt, where four people have died and 166 others have been infected, has ordered the closure of all cafes and shopping malls from dawn until dusk.
Saudi Arabia, which has reported 171 cases, has said it will cut government spending by 5%, or about $13.3bn, to offset the significant drop in global oil prices and the impact of the outbreak on its economy.

Modern slavery probe after woman found on Salford street


Littleton Road in SalfordImage copyrightGOOGLE
Image captionThe Vietnamese woman was found on Littleton Road in Salford on 5 March
A woman escaped a house where she was forced to be a sex worker and was found walking the streets more than 24 hours later, police have said.
The Vietnamese woman was found on Littleton Road in Salford at 05:30 GMT on 5 March after a member of the public contacted Greater Manchester Police.
"This woman has endured a terrifying, life-changing experience," Det Insp Yanica Weir said.
Police have appealed for information as part of a probe into modern slavery.
The woman told them she had taken three buses to escape from an unknown property.
Members of the public offered the woman food and money after she asked for help.
Det Insp Weir said specialist officers were supporting the woman through "this incredibly distressing time".
"We are carrying out a number of inquiries in an attempt to trace the property where the woman was being held and would urge anyone with any information about this to get in touch as soon as possible." 
Officers are keen to speak to anyone who recalls seeing the woman or talking to her between 03:00 on 4 March and 05:30 on 5 March.

Thursday, 19 March 2020

Hotel used for coronavirus quarantine collapses in China


Reuters/Shanghai
Filed on March 7, 2020 | Last updated on March 7, 2020 at 06.21 pm
hotel, quarantine, collapse, china, coronavirus
(Twitter)

Around 70 people are trapped under the rubble.

About 70 people were trapped on Saturday after a five-storey hotel being used for coronavirus quarantine collapsed in the port city of Quanzhou in southeast China, state media said.
A live video stream posted by the government-backed Beijing News site showed rescue workers in orange overalls clambering over mounds of rubble and carrying people towards ambulances gathered around the site.
Beijing News said the Quanzhou Xinjia Hotel had been five storeys high.
It collapsed at about 7:30 p.m. (1130 GMT) and 34 people were rescued in the following two hours, the Quanzhou municipality said on its website.
No reason was given for the collapse.
A woman named only by her surname, Chen, told the news site that relatives including her sister had been under quarantine at the hotel as prescribed by local regulations after returning from Hubei province, the centre of the coronavirus outbreak.
She said they had arrived on Feb. 25 and had been scheduled to leave soon after completing their 14 days of quarantine.
"I can't contact them, they're not answering their phones, she said.
"I'm under quarantine too (at another hotel) and I'm very worried, I don't know what to do. They were healthy, they took their temperatures every day, and the tests showed that everything was normal."
The official People's Daily said the hotel had opened in June 2018 with 80 rooms.
Quanzhou is a port city on the Taiwan Strait in the province of Fujian with a population of more than 8 million.
The Fujian provincial government said that as of Friday, the province had 296 cases of coronavirus and 10,819 people had been placed under observation after being classified as suspected close contacts.
The official Xinhua News Agency said the committee responsible for working safety under the State Council, China's cabinet, has sent an emergency working team to the site.

Covid-19: UAE suspends entry of all residents currently overseas


Wam
Filed on March 19, 2020 | Last updated on March 19, 2020 at 06.11 am
UAE coronavirus , suspends entry of residency visa,  residency visa,Wuhan, Covid-19, health, China,
(Photo by Shihab/KT)

The decision comes as part of the preventive and precautionary measures taken to contain the spread of Covid-19.

The UAE has suspended the entry of all its valid visa holders, who are currently out of the country, for a renewable period of two weeks effective 12.00 noon of Thursday, March 19, due to the spread of Covid-19. (Coronavirus outbreak: All the latest updates) 
The development comes as a precautionary measure to ensure the safety of those affected by the decision, which is subject to renewals depending on the health status measures taken due to the novel coronavirus outbreak.
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The Ministry of Foreign Affairs and International Cooperation has requested those holding valid UAE visas, and now staying out of the country, to pursue the following procedures:
-Those who are now staying in their countries of origin have to contact the UAE diplomatic missions in their respective nations for all necessary support and to streamline their return back to the UAE.
-Those who are currently outside the UAE for business considerations have to contact their employers here as well as Emirati diplomatic missions in their host countries for all necessary support to facilitate their return back to the UAE.
-Those who are now on vacation have to contact UAE diplomatic missions in their respective host countries for all necessary support to facilitate their return back to the UAE.
The Federal Authority for Identity and Citizenship (ICA) has urged the families and kins of those affected by the decision to get in touch with the ICA via the following contact numbers to get updated on all the measures they have to pursue:
-Fax: 025543883
-Mobile: 0501066099
-Landline 02 3128867- 02 3128865
In a statement today, ICA said the new decision comes as part of the preventive and precautionary measures taken to contain the spread of Covid-19.

Coronavirus: PIA plans to send special flights to UAE to bring back Pakistanis


Muzaffar Rizvi/Dubai
Filed on March 19, 2020 | Last updated on March 19, 2020 at 03.40 pm
PIA, Pakistan international airlines, covid-19, coronavirus, Lahore, Karachi, Abu Dhabi, Dubai, Sharjah
(alamy.com/ae)

The flights will fly to Abu Dhabi, Dubai and Sharjah.

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Pakistan International Airlines (PIA) is in talks with the UAE authorities to get permission for special flights to bring back overseas Pakistanis in the emirate, an airline spokesman said.
He said the PIA has suspended its regular flight operations to the UAE.
"We have closed booking for the UAE destinations and informed all PIA officers and travel agents," the spokesman said.
"The PIA special flights will fly to Dubai, Abu Dhabi and Sharjah and bring back Pakistanis in the UAE," the spokesman said.
He said PK203 from Lahore to Dubai, PK263 from Lahore to Abu Dhabi and PK293 have already left without passengers to their respective destinations," he said, adding that PK213 will also fly without passengers from Karachi to Dubai.
"We are updating all booked passengers from the UAE through call centres about the latest developments and status of special flights," the PIA spokesman said.
Meanwhile, the airline sources said PIA incurred a loss of over Rs4 billion due to suspension of its flight operations amidst coronavirus outbreak.
Pakistan Civil Aviation Authority (CAA) also suffered Rs2.5 billion loss during the last 10 days due to the suspension of domestic and international flights, the sources said.
An airline official said that empty PIA aircraft were also being sent to Saudi Arabia to bring back the Pakistani pilgrims.
muzaffarrizvi@khaleejtimes.com

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