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Residents of Nalgonda in India's newly-formed state of Telangana are used to high temperatures during the summer months.
But the intensity of this heatwave has left businessman Ravinder Reddy confined to his house for a full week.
"Two of my employees are in hospital due to heat strokes," he told the BBC.
Ahmed Pasha, who cultivates 12 acres of land, says there is no water in the well or in the bore-hole.
"It has all gone so dry that more than 50% of the grass that I had grown for the buffaloes and the goats has dried up.
"The majority of the victims are people who have been exposed to the sun directly, usually aged 50 and above and from the working classes," news agency AFP quoted P Tulsi Rani, special commissioner of Andhra Pradesh's disaster management department, as saying.
"We are asking them to take precautions like using an umbrella, using a cap, taking a huge quantity of liquids like water and buttermilk, and wearing cotton clothing," he added.
The Press Trust of India (PTI) news agency said the heatwave had killed 186 people in 10 districts in neighbouring Telangana state, with 58 people dying since Saturday.
The north-western desert state of Rajasthan has also recorded several deaths due to the heat, the PTI reported, including a woman who collapsed and died on a roadside in Bundi city.
The meteorological department said the sweltering conditions were likely to continue for a few more days.
"No relief" is expected in Andhra Pradesh, Telangana, Delhi and other northern states for the next four days, and the "heatwave will continue," an official said.
Reports said at least 10 people had died of the heat in the eastern state of West Bengal.
Non air-conditioned taxis will be taken off the road for five hours during the day in the main city in the state capital, Kolkata, after two drivers died from heat stroke.
Meteorological officials said the heatwave was due to a lack of rain.